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Trimetazidine can cause or worsen parkinsonian symptoms (tremor, akinesia, hypertonia), which should be regularly investigated, especially in elderly patients. In doubtful cases, patients should be referred to a neurologist for appropriate investigations.

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Caution should be exercised when prescribing trimetazidine to patients in whom an increased exposure is expected: moderate renal impairment (see Pharmacology: Pharmacokinetics under Actions and Dosage & Administration), elderly patients older than 75 years old (see Dosage & Administration).

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Effective tax rate for Q1 2023 has also been incorporated into guidance Vastarel 20 mg no prescription. Q1 2023, primarily driven by net losses on equity securities. The conference call will Vastarel 20 mg no prescription begin at 10 a. Eastern time today and will be available on this same website for approximately 90 days. Net other income (expense) 35.

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